منابع مشابه
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors.
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze sphingomyelin and glycerophospholipids, respectively, generating products identical to the ones produced by eukaryotic enzymes which play crucial roles in distinct physiologic...
متن کاملTracking bacterial virulence: global modulators as indicators
The genomes of Gram-negative bacteria encode paralogues and/or orthologues of global modulators. The nucleoid-associated H-NS and Hha proteins are an example: several enterobacteria such as Escherichia coli or Salmonella harbor H-NS, Hha and their corresponding paralogues, StpA and YdgT proteins, respectively. Remarkably, the genome of the pathogenic enteroaggregative E. coli strain 042 encodes...
متن کاملComparative Kinetics of Hemolysis Induced by Bacterial and Other Hemolysins
A study has been made of the kinetics of lysis induced by various hemolytic agents. The course of bemolysis was followed by mixing lysin with washed human erythrocytes, removing samples from the mixture, and estimating colorimetrically the hemoglobin in the supernatant fluid of the centrifuged samples. Most of the curves (but not all of them, e.g. tyrocidine) obtained by plotting degree of hemo...
متن کاملTissue Hemolysins as Lysin-inhibitor Complexes
1. Lytic substances are enzymatically produced at 37 degrees C. from tissue slices or homogenates (mouse liver, kidney, etc.) and appear in the medium in which the tissue fragments are suspended. Their concentration increases with the time during which the tissue is kept at 37 degrees C. (preincubation), and is accompanied by pH changes, so that the lytic activity as finally measured is a funct...
متن کاملDo Bacterial “Virulence Factors” Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in Pseudomonas aeruginosa As a Test Case
Bacterial traits that contribute to disease are termed "virulence factors" and there is much interest in therapeutic approaches that disrupt such traits. What remains less clear is whether a virulence factor identified as such in a particular context is also important in infections involving different host and pathogen types. Here, we address this question using a meta-analytic approach. We sta...
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ژورنال
عنوان ژورنال: Antonie van Leeuwenhoek
سال: 1988
ISSN: 0003-6072,1572-9699
DOI: 10.1007/bf00461864